An 18-year-old has died and a 16-year-old has been seriously injured after they were stabbed at a skate park in Weston overnight.

At about 1am this morning ACT Emergency Services were called to the Dillon Close following reports of a stabbing.

ACT Ambulance Service paramedics treated the two young men but an 18-year-old man with multiple stabbing injuries died at the scene.

A 16-year-old was taken to hospital with serious injuries and was underwent emergency surgery this morning.

It was unclear if the two men were known to each other, police said.

A crime scene was established on Dillon Close, just off Namatjira Drive, where emergency services have remained for most of the day.

Detective Acting Superintendent Mark Steel said police want to speak with a person who made a phone call to emergency services this morning about the attack.

"It was a call to triple-0, requesting police and ambulance at the scene," he said.

"It's a secluded area down here at the Weston skate park … we're still investigating how many people were involved.

"There could be other people involved, and that's why we're appealing for any information."

The investigation into how the stabbings occurred is continuing.

Anyone who witnessed the incident or who has information that could help police is urged to contact Crime Stoppers on 1800 333 000, or via the Crime Stoppers ACT website. Please quote reference P2001072. Information can be provided anonymously.